I can only say that your GP was right. More rest needed. This is one of the very strong signals that a person with ME has to recognise. It is the bodies way of telling you you need rest. That you need it NOW and not in five minutes or when it is convenient. It is NOW. Your lady will need to learn the skill of pacing. It is a skill that does not come naturally to everyone, but needs to become a way of life and be in the forefront of your daily being. It might sound harsh advice, but believe me once you get the hang of it, pacing can and does improve your day.